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Glossary

Maintenance

Maintenance can be defined as a process whereby the patient is kept on a minimal, but effective dosage for a long period of time. This process is done to ensure that the recovering addict is ready for long term abstinence.

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Monotherapy

Monotherapy is a type of therapy where only one form of treatment or drug is used.

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Mu Agonist

MU agonists are drugs that bind to and stimulate the m1 and m2 brain receptor. The opioids also attach themselves to the spinal cord and thrive under conditions such as inflammation.

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Mu Opioid Receptor

Found on the membrane of nerve cells, mu opioid receptors acts as a ‘middle-man’ to opioid analgesia, opioid tolerance and addiction. When opioid agonists bind to the mu opioid receptor, proteins linked with the signalling activates.

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Narcotic Addict Treatment Act (NATA)

The Narcotic Addiction Treatment Act (NATA) of 1974 authorized the use of methadone in opioid addiction treatment; however it made the use of off-label opioids illicit.

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Negative Reinforcement

Negative reinforcement can be defined as repetitive actions in order to avoid negative effects. In drug terms, an example would be an individual addicted to a narcotic substance and continues to use it excessively in order to ward off withdrawal symptoms.

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